ReFissa RX 40g

ReFissa RX 40g





Available only by prescription, ReFissa 40g is the only FDA-approved prescription cream with a 0.05% tretinoin emollient base designed to reduce facial wrinkles, correct irregular pigmentation, and smooth substantial skin roughness. 


  • Apply with Melamix to affected areas twice a day or as directed by a physician. Always follow with sunscreen protection. See enclosed package insert for full prescribing information.